Here is the 210 mile loop I mentioned that dips into WV from southwestern PA. Most of the route is big bike friendly but you better have some TKC80s, skills, and a buddy for backup for the gnarly bits. Thumpers (KLR650 and smaller) recommended for the most fun. There are two parking lots at the beginning of the route on either side of route 31 if you want to truck/trailer to the loop. Lunch/gas is at 110 miles in Kingwood, but there are several other spots to stop along the way. It’s a full day (9 hours with breaks?) but really good fun and a nice mix of roads.
NOTE #1: You can shorten the route and skip the gnarliest stuff by not venturing south of I-68. You can just short-circuit the route and cut directly over to Bruceton Mills (CR-73) or take some dirt roads over to Bruceton Mills.
NOTE #2: There are a few short options for more adventure along the way if you want more challenge.